Nyligen så gjorde Tim Schafer (Grim Fandango, Full Throttle, mfl.) en AMA (Ask Me Anything) på Reddit angående Psychonauts 2. När Schafer blev tillfrågad angående uppföljarens story så berättade han en hel del om vad vi kan förvänta oss i denna efterlängtade tvåa:
"In Psychonauts 2, Raz will finally get to go to Psychonauts headquarters-his lifelong dream. There he can see Sasha and Milla in their natural environment-international espionage. But he finds several things strange about the organization. While Truman Zanotto was missing, several changes to the direction of the organization were made by his second in command. Funding was cut from traditional psychic research and peacekeeping, and redirected to unorthodox, fringe endeavors, including the discredited practice of necromancy. Raz soon uncovers sinister things at work in the shadows of Psychonauts headquarters, including double agents and evils of the past. Raz's own family history plays a pivotal part in the story, and Raz must confront the roots of the curse placed on his family once and for all. And also deal with this whole 'girlfriend' term and what it really means"